Murrells Inlet Homes with Office Property Subtype

Welcome to Murrells Inlet, South Carolina – a hidden gem nestled along the stunning coastline of the Grand Strand. Known for its picturesque marsh views, vibrant seafood culture, and charming small-town atmosphere, Murrells Inlet is the perfect blend of relaxation and recreation. This quaint coastal community is renowned for its scenic waterfront, where you can indulge in fresh catches from local restaurants or embark on a fishing adventure. With beautiful parks, nature trails, and proximity to pristine beaches, residents enjoy an outdoor lifestyle that’s hard to resist.

For those seeking a home that caters to both work and leisure, Murrells Inlet offers an enticing selection of homes with office property subtypes. Imagine having a dedicated workspace right within your own sanctuary, allowing you to balance productivity and comfort seamlessly. These thoughtfully designed homes provide ample space for a home office, whether you’re running a business, pursuing creative endeavors, or simply need a quiet place to concentrate.

With the tranquil backdrop of marshland or ocean views, your workspace can inspire creativity and productivity. Enjoy the convenience of working from home while being just minutes away from the area's stunning beaches, golf courses, and nature preserves.

Murrells Inlet is more than just a place to live; it’s a lifestyle. Whether you're an entrepreneur, a remote worker, or someone who simply values a home office, you’ll find the ideal residence that meets your needs in this enchanting coastal town. Discover the perfect blend of work and play in Murrells Inlet today!

Newest Murrells Inlet Homes with Office Property Subtype

$17,100

2617884 MLS

For Lease: turn-key freestanding medical office on 1.3 acres. Located at the corner of US-17 Bus and Eden Ave in Murrells Inlet near Ortho SC and Tidelands Health Waccamaw Community Hospital. Excellent ingress/egress with full access from US 17. Space consists of large lobby/waiting room, reception office, 4 exam rooms, 3 procedure rooms, doctor's office, nurses station, x-ray room, 4 restrooms, break room and multiple storage rooms. Pylon sign with digital board. Located within the Murrells Inlet submarket in Georgetown County near medical, retail, and high density residential. The Myrtle Beach MSA has been one of fastest growing MSA's in the US for the past 4 years. Permanent population within a 5 mile radius is 63,220. Average Daily Traffic on Hwy 17 is 41,900. Inlet Square Mall (Hobby Lobby, Belk, Floor & Decor, Planet Fitness, 2 new hotels, etc.) is located just north of subject property. Also, a new 4 story luxury apartment complex was recently completed on the opposite side of Hwy 17.

3583 Highway 17 Business Unit Former Southern Urgent Ca, Murrells Inlet

Listing courtesy of Listing Agent: Drew Parks () from Listing Office: CB Sea Coast Commercial.

$525

2615968 MLS

Looking establish a business presence in Murrells Inlet? This well-appointed executive office suite offers a professional setting with access to a shared conference room and break area. Lease includes water, sewer and electric for added convenience. Ideal for a small business or satellite office, this office is prominently located directly on Highway 17 By Pass, Murrells Inlet, providing easy access.

3955 Highway 17 Bypass Unit Unit C, Murrells Inlet

Listing courtesy of Listing Agent: Deby Emanuel () from Listing Office: Exit Coastal Real Estate Pros.

$8,000

2615537 MLS

Class A Medical Office Space for Lease – Suite 103 4310 Highway 17 Bypass | Murrells Inlet, SC Suite 103 offers 3,557 square feet of premier Class A medical office space in one of Murrells Inlet's most advanced healthcare facilities. The Landlord is offering a generous Tenant Improvement Allowance, providing medical users the opportunity to customize the space to their exact operational and clinical requirements. Recently renovated throughout, the property is designed specifically to accommodate modern healthcare providers and offers a professional environment for physicians, specialists, outpatient services, and related medical uses. Tenants benefit from a comprehensive rental package with utilities, trash service, and janitorial service included in the rent, creating a highly efficient and predictable occupancy cost structure. The building features an impressive shared lobby designed to create a first-class patient experience, complete with a complimentary coffee bar and beverage station for patients and visitors. Additional amenities include dedicated patient and service elevators, monument signage opportunities, and approximately 160 parking spaces to comfortably accommodate patients and staff. The property is further enhanced by a Sentry 30 Security System, automatic water shut-off system after business hours, and a state-of-the-art Cosatron Air Purification System—a technology shared by only a select few facilities in the region, including Myrtle Beach International Airport. Further enhancing the property's medical ecosystem, a new surgery center is currently under construction on the second floor. Upon completion, the facility will feature nine pre-operative beds, nine post-operative recovery beds, and three operating rooms, including one lead-lined operating suite, creating a synergistic environment for physicians, surgeons, specialists, and ancillary healthcare providers. Conveniently located along the highly traveled Highway 17 Bypass corridor, the property offers excellent visibility, accessibility, and proximity to the rapidly growing Murrells Inlet, Garden City, Pawleys Island, and southern Grand Strand markets. Highlights- Ideal for medical and healthcare users Tenant Improvement Allowance Utilities, trash, and janitorial included in rent Recently renovated Class A medical building Shared lobby with complimentary coffee and beverage station Patient and service elevators Cosatron Air Purification System Sentry 30 Security System Automatic water shut-off system Monument signage available Approximately 160 parking spaces New ambulatory surgery center under construction Prime Highway 17 Bypass location in Murrells Inlet

4310 Highway 17 Business Unit Unit 103, Murrells Inlet

Listing courtesy of Listing Agent: Abernethy & Jones Commercial Group () from Listing Office: NAI The Litchfield Company.

$1,000

2614092 MLS

Excellent leasing opportunity in a highly visible professional office building along Highway 17 Bypass in Murrells Inlet. This move-in-ready second-floor suite offers approximately 863 square feet and features a functional layout with a reception/open workspace, two private offices, private restroom, and kitchenette. The property offers excellent accessibility with entrances from both Highway 17 Bypass and Coquina Avenue, including a dedicated curb cut for southbound traffic. Tenants and clients will appreciate the ample on-site parking, attractive building presence, and professionally maintained main lobby providing access to the second-floor office. Potential signage opportunities may be available, including building window signage and possible road-facing signage exposure, subject to landlord approval. Ideal for professional, medical, consulting, insurance, financial, real estate, or administrative users seeking a well-located office in the heart of the South Strand business corridor. Base rent plus triple net (NNN) expenses. Landlord prefers a minimum three-year lease term. Contact the listing agent for lease rates, signage details, and additional information.

4717 Highway 17 Bypass Unit Second Floor Office Space, Murrells Inlet

Listing courtesy of Listing Agent: Kyle Hawley () from Listing Office: Dunes Realty Sales.

$1,500

2610107 MLS

Discover an exceptional leasing opportunity in a highly desirable location. This approximately 1,000-square-foot gross lease space includes power and water in the monthly rent, offering predictable overhead for your business. Key Features & Layout: Two private offices, a spacious private conference room, a full private bathroom, and a large private kitchen/file room (includes two large file cabinets). Shared Amenities: A welcoming shared lobby and a prominent marquee signage slot to maximize your business exposure. Parking & Accessibility: Ample shared parking at the front of the building. Special Incentive: Receive one month of free rent with a signed 12-month lease. Co-Tenants: The other half of the building is occupied by an established, long-term counseling business. All other listed spaces are strictly for your private use. The owner is a licensed South Carolina Broker-in-Charge (BIC). The previous tenant is currently transitioning out. PLEASE DO NOT DISTURB THE CURRENT TENANTS. The rear yard is available for lease, MLS#2506776. Contact your agent to schedule a private showing today!

889 Inlet Square Dr., Murrells Inlet

Listing courtesy of Listing Agent: Paige Kennedy (pkennedy@carolinarealestateservices.com) from Listing Office: Carolina Real Estate Services.

$3,670

2607997 MLS

Excellent opportunity to lease professional office space in the heart of Murrells Inlet with convenient access to both Highway 17 Business and Highway 17 Bypass. This well-maintained property offers strong accessibility, ample on-site parking, and monument signage available for each unit, providing excellent visibility for tenants. The building offers 3,000 SF total available, which can be leased as a single space or divided into 1,000 SF and 2,000 SF suites to accommodate a variety of professional users. The 2,000 SF suite is well designed for professional office use and features a welcoming reception area, conference room, multiple large executive offices, and nicely appointed office finishes throughout. The suite also includes approximately 600 SF of unfinished second-floor storage space, offering an excellent opportunity for future expansion into additional office space if desired. Tenants will also benefit from nicely appointed offices, dedicated break room areas, and functional layouts that can accommodate a range of professional or service-oriented businesses. Ownership is willing to provide a Tenant Improvement (TI) Allowance to assist with customization and tenant upfit. This is an ideal location for professional office, medical, or service-based users seeking quality space with excellent access and visibility in one of the Grand Strand’s most desirable business corridors.

5187 Horry Dr. Unit Unit B, Murrells Inlet

Listing courtesy of Listing Agent: Abernethy & Jones Commercial Group () from Listing Office: NAI The Litchfield Company.

$1,875

2605025 MLS

For Lease: 900 SF office suite in Grandhaven Center, a professional office complex off Hwy 17 Bypass in Murrells Inlet. Suite consists of small reception area, three private offices, two restrooms, and kitchenette. Located just north of Inlet Square Mall. Easily accessible via Hwy 17 Bypass and Hwy 17 Bus via Inlet Square Dr. Located within the Murrells Inlet submarket in Horry County. The Myrtle Beach MSA has been one of fastest growing MSA's in the US for the past 3+ years. Permanent population within a 5-mile radius is 75,075. Average Daily Traffic on Hwy 17 Byp is 36,500. Inlet Square Mall, just south of subject property on Hwy 17 Byp, is under redevelopment, with Hobby Lobby, Floor & Decor, Planet Fitness, Belk, and 2 new hotels. A new 4 story luxury apartment complex was recently completed on the frontage road just south of the subject property.

11945 Grandhaven Dr. Unit Suite D, Murrells Inlet

Listing courtesy of Listing Agent: Drew Parks () from Listing Office: CB Sea Coast Commercial.

$3,000

2603477 MLS

Carney Center is a new multi-building flex development in the heart of Murrells Inlet offering exceptional visibility, access, and functionality for a wide range of commercial users. Four new construction buildings are currently underway, providing tenants the opportunity to secure space early and customize interiors to meet specific operational needs. This prime Highway 17 Bypass location features excellent exposure, ample parking, prominent signage opportunities, and convenient access for both customers and business owners. The development showcases attractive Lowcountry-inspired architecture with brick, Hardie plank siding, and metal accents, creating a clean, professional aesthetic with strong curb appeal. Front Buildings (Buildings 1 & 2) Divisible into: ±1,625 SF, ±2,250 SF, ±4,875 SF, or full ±6,500 SF suites ±6,500 SF each Rear roll-up garage doors included in all units Designed to accommodate office, showroom, and flex users Strong highway visibility and signage opportunities Rear Buildings (Buildings 3 & 4) ±6,500 SF each Divisible into: ±1,625 SF, ±2,250 SF, ±4,875 SF, or full ±6,500 SF suites Front roll-up doors with man doors for convenient access Ideal for service, storage, light industrial, or support operations Property Highlights New construction with tenant build-to-suit flexibility Ample on-site parking Excellent ingress/egress and circulation Functional layouts for office, showroom, warehouse, and service uses Roll-up doors included in all units Opportunity to lease front and rear units together for operational efficiency Carney Center is well-suited for contractors, service providers, medical or professional users, showroom operators, light industrial tenants, and businesses seeking a flexible, high-visibility Murrells Inlet location. Call today for availability, spec sheets, and pricing details—and secure your space before leasing is complete.

4960 Highway 17, Murrells Inlet

Listing courtesy of Listing Agent: Abernethy & Jones Commercial Group () from Listing Office: NAI The Litchfield Company.

$525

2600053 MLS

3955 Highway 17 Bypass Unit Unit B, Murrells Inlet

Listing courtesy of Listing Agent: Deby Emanuel () from Listing Office: Exit Coastal Real Estate Pros.

$650

2522219 MLS

For Lease: 10x15 office on the 2nd floor (no elevator) of professional office building in Murrells Inlet. Common restroom and kitchenette. Located east of Hwy 17 near the Wachesaw Rd intersection, in close proximity to Tidelands Health Waccamaw Hospital. Ground Floor is occupied by MD 4 Vitality, Hair Health and 2 attorneys. Located within the Murrells Inlet submarket in Georgetown County. The Myrtle Beach MSA has been one of fastest growing MSA's in the US for the past 3 years. Permanent population within a 5 mile radius is 40,357.

641 Little Tony Ave. Unit 2nd Floor, Suite 3, Murrells Inlet

Listing courtesy of Listing Agent: Drew Parks () from Listing Office: CB Sea Coast Commercial.

$650

2522209 MLS

For Lease: 12x16 office on the 2nd floor (no elevator) of professional office building in Murrells Inlet. Common restroom and kitchenette. Located east of Hwy 17 near the Wachesaw Rd intersection, in close proximity to Tidelands Health Waccamaw Hospital. Ground Floor is occupied by MD 4 Vitality, Hair Health and 2 attorneys. Located within the Murrells Inlet submarket in Georgetown County. The Myrtle Beach MSA has been one of fastest growing MSA's in the US for the past 3 years. Permanent population within a 5 mile radius is 40,357.

641 Little Tony Ave. Unit 2nd Floor, Suite 1, Murrells Inlet

Listing courtesy of Listing Agent: Drew Parks () from Listing Office: CB Sea Coast Commercial.

Start Your Search

Provided courtesy of The Coastal Carolinas Association of REALTORS®. Information Deemed Reliable but Not Guaranteed. Copyright 2026 of the Coastal Carolinas Association of REALTORS® MLS. All rights reserved. Information is provided exclusively for consumers’ personal, non-commercial use, that it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.

Copyright 2026 NCRMLS. All rights reserved. North Carolina Regional Multiple Listing Service, (NCRMLS), provides content displayed here (“provided content”) on an “as is” basis and makes no representations or warranties regarding the provided content, including, but not limited to those of non-infringement, timeliness, accuracy, or completeness. Individuals and companies using information presented are responsible for verification and validation of information they utilize and present to their customers and clients. NCRMLS will not be liable for any damage or loss resulting from use of the provided content or the products available through Portals, IDX, VOW, and/or Syndication. Recipients of this information shall not resell, redistribute, reproduce, modify, or otherwise copy any portion thereof without the expressed written consent of NCRMLS.